Helicobacter pylorivacA genotype is a predominant determinant of immune response toHelicobacter pyloriCagA

Helicobacter pylori vacA genotype is a predominant determinant of immune response to Helicobacter pylori CagA

AIM To evaluate the frequency of Helicobacter pylori (H. pylori) CagA antibodies in H. pylori infected subjects and to identify potential histopathological and bacterial factors related to H. pylori CagA-immune response. METHODS Systematic data to H. pylori isolates, blood samples, gastric biopsies for histological and molecular analyses were available from 99 prospectively recruited subjects...

Immune Response to Helicobacter pylori

Immune Response to Antigenic Determinant of Tmvp

The recent use of chemically defined polypeptides to investigate immunological phenomena has resulted in a wealth of information regarding the chemical and biological basis of antigenicity, immunogenicity, skin reactivity, and cell-antigen interactions. Information obtained from chemically defined systems is more meaningful and comprehensive than that obtained from the chemically ill-defined sy...

Hepatitis B Virus Genotype C is Predominant in Myanmar

Myanmar is adjacent to India, Bangladesh, Thailand, Laos and China. In Myanmar, the prevalence of hepatitis B virus (HBV) infections is 6.5% and accounts for 60% of hepatocellular carcinoma. HBV has nine genotypes that have been identified by molecular genetic analysis. HBV genotypes are associated with several clinical features. We reviewed the prevalence of HBV genotypes in Myanmar and neighb...

Local Immune Response in Helicobacter pylori Infection

There have been few studies concerning the cytokine profiles in gastric mucosa of Helicobacter pylori-infected patients with normal mucosa, chronic gastritis, and gastric carcinoma (GAC).In the present study, we aimed to elucidate the genomic expression levels and immune pathological roles of cytokines-interferon (IFN)-γ, tumor necrosis factor (TNF)-α, interleukin (IL)-4, IL-6, IL-10, transform...